Astepro® spectrum

 

WITH MORE ADVANCED OTC ASTEPRO® ALLERGY, YOU CAN LEAVE
THE RX* BEHIND

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MAXIMUM STRENGTH

Azelastine HCI (0.15%) has a 50% higher concentration per spray than Rx azelastine 0.10%1-4

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IMPROVED TASTE 

Includes a sweetener to improve its taste profile versus Rx azelastine 0.10%1,2,5 

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LONGER DURATION 

Offers nasal symptom relief for up to 24 hours, while Rx azelastine 0.10% only has a 12-hour indication1,4 

EXPLORE THE ADVANTAGES OF OTC ASTEPRO® OVER RX AZELASTINE 0.10%

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Muscle icon

MAXIMUM STRENGTH

ASTEPRO® demonstrates a higher concentration of azelastine in the blood vs Rx azelastine 0.10%.6

MEAN ± SD PHARMACOKINETIC PARAMETERS FOLLOWING 2 SPRAYS OF 0.10% RX AZELASTINE (548 MCG),
AND 0.15% ASTEPRO (822 MCG) SOLUTION PER NOSTRIL6

Astepro AUC chart vs Rx

Study design: Phase 1, open-label, single-center, randomized, parallel-group relative bioavailability study (N=54) of 3 intranasal formulations (2 sprays per nostril) of azelastine HCl: 0.10% Astelin® (total dose: 548 mcg), 0.10% ASTEPRO® (548 mcg), and 0.15% ASTEPRO® (822 mcg).

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Mouth and tongue icon

IMPROVED TASTE

Includes a sweetener to improve its taste profile vs Rx azelastine 0.10%. In clinical trials, 94% of patients receiving Astepro® reported no bitter taste.1,2,5

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24-hour clock icon

LONGER DURATION

OTC ASTEPRO® can be dosed once per day and is indicated for 24-hour relief, while Rx azelastine 0.10% is only indicated for 12-hour relief, requiring twice per day dosing to achieve 24-hour relief.1,4

One bottle of OTC ASTEPRO® can potentially provide relief for twice as long as an equivalent bottle of Rx azelastine 0.10%.†

†Based on bottles with 200 metered sprays, OTC Astepro used once a day (one spray per nostril) versus Rx azelastine 0.10% used twice a day (one spray per nostril).

SEE HOW ASTEPRO® COMPARES WITH RX AZELASTINE 0.10%

Astepro chart vs Rx

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REFERENCES: 
1. NDA 213872.  2. Astepro®. Prescribing information. Meda Pharmaceuticals Inc; 2018.  3. US Department of Health and Human Services. Pediatric Postmarketing Pharmacovigilance and Drug Utilization Review. November 3, 2016. Accessed February 28, 2024.  4. Astelin. Prescribing information. Meda Pharmaceuticals Inc; 2014. 5. van Bavel J, Howland WC, Amar NJ, Wheeler W, Sacks H. Efficacy and safety of azelastine 0.15% nasal spray administered once daily in subjects with seasonal allergic rhinitis.  Allergy Asthma Proc. 2009;30(5):512-518. doi:10.2500/aap.2009.30.3284 6. NDA 22371.